ABOUT US

Shanghai Puyou Biomedical Co., Ltd.

With a location in Zhangjiang Science Park,Zhoupu,Shanghai,Puyou focuses on the world's first-in-class therapies for treating various diseases caused by protein conformational changes with huge unmet medical needs. The company strives to be an innovation-driven global biotech company, in China and for the world.

The pipelines of Puyou are built mainly by internal independent research with proprietary intellectual properties, supported by external co-development and license-in. With a patient-oriented strategy to address unmet medical needs, Puyou develops several novel therapies with different formulations to cover ophthalmic diseases, metabolic diseases, chronic inflammation diseases, and neurodegenerative diseases. We aim to be a pioneer and leader in 2-3 disease areas global wide. Currently Puyou holds the global rights to four first-in-class product candidates, and the Investigational New Drug (IND) application for dry eye disease (DED) was approved by FDA and CDE in 2023 respectively. Phase I study result showed CF04 ophthalmic solution was safe and well tolerated in healthy subjects with no TEAEs related to the investigational product. Currently, proof-of-concept phase II study was initiated in China, and is expected to complete subject enrollment in Mar 2025.

Strength and highlights

Currently Puyou holds the global rights to four first-in-class product candidates, and the Investigational New Drug (IND) application for dry eye disease (DED) was approved by FDA and CDE in 2023 respectively. Phase I study result showed CF04 ophthalmic solution was safe and well tolerated in healthy subjects with no TEAEs related to the investigational product. Currently, proof-of-concept phase II study was initiated in China, and is expected to complete subject enrollment in Mar 2025.

  • Novel mechanisms
  • Excellent safety profile
  • Strong IP protection
  • Huge market potential

History





2014 Seed Fund
2016 First PCT patent submission
2018 Pre-A Fund
2020 The mechanism was confirmed by primate model
2022 Construction of a new 3,700㎡ facility
2023 First IND application、IND approval by CDE
2024 Completed Phase I and Initiated Phase II

Management team

Yinghao Zhang Founder, Chairman of the Board
PhD, Chinese Academy of Sciences
20 years’ experience in pharma industry
7 academic papers
50+ patents

Guirui Yan Senior Director, Pre-Clinical Research
PhD, Chinese Academy of Sciences
15 years’ experience in pharma industry
Former preclinical team leader at Lilly China
8 invention patents

Rongxun Sun Director, CMC
MS, Chinese Academy of Sciences
14 years’ experience in pharma industry
Strong expertise in CMC

Hongwei Luo Director,Medicine
MS, Hiroshima University
20 yrs in clinical & medical
50+ projects experiencesClinical lead in Otsuka and Sumitomo